Published 05 Mar 2026

The Evolution of Lipid Nanoparticles in Targeted Drug Delivery

Author: Mr. Junaed Alom • RxInk Editorial Board

Over the past decade, lipid nanoparticles (LNPs) have emerged as the premier delivery vehicle for therapeutic oligonucleotides, fragile peptide drugs, and targeted chemotherapy agents.

Ionizable Lipids and Cellular Uptake

The strategic incorporation of pH-sensitive ionizable lipids enables efficient endosomal escape without triggering severe systemic immunogenicity.